PDBe 5gwn

X-ray diffraction
1.31Å resolution

Crystal structure of human RCC2

Released:
Source organism: Homo sapiens
Primary publication:
RCC2 is a novel p53 target in suppressing metastasis.
OpenAccess logo Oncogene (2017)
PMID: 28869598

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein RCC2 Chain: A
Molecule details ›
Chain: A
Length: 439 amino acids
Theoretical weight: 47.96 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9P258 (Residues: 89-522; Coverage: 83%)
Gene names: KIAA1470, RCC2, TD60
Sequence domains: Regulator of chromosome condensation (RCC1) repeat

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 94.447Å b: 84.056Å c: 60.671Å
α: 90° β: 101.57° γ: 90°
R-values:
R R work R free
0.172 0.171 0.189
Expression system: Spodoptera frugiperda