PDBe 5grd

X-ray diffraction
1.8Å resolution

Crystal structure of 10-mer peptide from EBV in complex with HLA-A1101.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-11 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13746 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-A, HLAA
Sequence domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Latent membrane protein 2 Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 999 Da
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P13285 (Residues: 340-349; Coverage: 2%)
Gene name: LMP2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P212121
Unit cell:
a: 54.422Å b: 67.795Å c: 115.295Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.226
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided