PDBe 5gmv

X-ray diffraction
2.25Å resolution

LC3B-FUNDC1 complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Microtubule-associated proteins 1A/1B light chain 3B Chains: A, B
Molecule details ›
Chains: A, B
Length: 125 amino acids
Theoretical weight: 14.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q9GZQ8 (Residues: 1-125; Coverage: 100%)
Gene names: MAP1ALC3, MAP1LC3B
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
FUN14 domain-containing protein 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 1.03 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8IVP5 (Residues: 16-23; Coverage: 5%)
Gene name: FUNDC1

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 40.537Å b: 86.85Å c: 40.537Å
α: 90° β: 110.86° γ: 90°
R-values:
R R work R free
0.209 0.206 0.272
Expression systems:
  • Escherichia coli K-12
  • Not provided