PDBe 5fxr

X-ray diffraction
2.4Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-like growth factor 1 receptor beta chain Chain: A
Molecule details ›
Chain: A
Length: 308 amino acids
Theoretical weight: 35.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08069 (Residues: 980-1286; Coverage: 23%)
Gene name: IGF1R
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF
Spacegroup: P212121
Unit cell:
a: 41.252Å b: 67.331Å c: 122.166Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.227 0.294
Expression system: Escherichia coli