PDBe 5fbh

X-ray diffraction
2.7Å resolution

Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Extracellular calcium-sensing receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 568 amino acids
Theoretical weight: 64.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
  • Canonical: P41180 (Residues: 20-541; Coverage: 49%)
Gene names: CASR, GPRC2A, PCAR1
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: C2
Unit cell:
a: 172.107Å b: 83.106Å c: 94.47Å
α: 90° β: 105.15° γ: 90°
R R work R free
0.184 0.182 0.236
Expression system: Homo sapiens