PDBe 5fa3

X-ray diffraction
1.86Å resolution

Structure of HLA-A2:01 with peptide G9V

Released:
Source organisms:
Entry authors: Zajonc DM, Remesh SG

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
G9V Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 908 Da
Source organism: Toxoplasma gondii
Expression system: Not provided
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
HLA class I histocompatibility antigen, A-2 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 31.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01892 (Residues: 26-298; Coverage: 80%)
Gene names: HLA-A, HLAA
Sequence domains: Immunoglobulin C1-set domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 56.201Å b: 79.259Å c: 57.397Å
α: 90° β: 115.98° γ: 90°
R-values:
R R work R free
0.211 0.21 0.235
Expression systems:
  • Not provided
  • Escherichia coli