PDBe 5es4

X-ray diffraction
3.3Å resolution

RE-REFINEMENT OF INTEGRIN ALPHAXBETA2 ECTODOMAIN IN THE CLOSED/BENT CONFORMATION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-X Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 1137 amino acids
Theoretical weight: 125.61 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P20702 (Residues: 20-1103; Coverage: 95%)
Gene names: CD11C, ITGAX
Sequence domains:
Integrin beta-2 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 727 amino acids
Theoretical weight: 80.63 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P05107 (Residues: 23-696; Coverage: 90%)
Gene names: CD18, ITGB2, MFI7
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 132.03Å b: 163.48Å c: 536.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.257 0.307
Expression system: Cricetulus griseus