PDBe 5era

X-ray diffraction
3.8Å resolution

Human Connexin-26 (Calcium-free)

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo 12-mer
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gap junction beta-2 protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 226 amino acids
Theoretical weight: 26.14 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P29033 (Residues: 1-226; Coverage: 100%)
Gene name: GJB2
Sequence domains: Connexin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: R32
Unit cell:
a: 155.727Å b: 155.727Å c: 160.699Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.304 0.3 0.333
Expression system: Spodoptera frugiperda