PDBe 5eqi

X-ray diffraction
3Å resolution

MFS transporter in complex with Cytochalasin B

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier family 2, facilitated glucose transporter member 1 Chain: A
Molecule details ›
Chain: A
Length: 492 amino acids
Theoretical weight: 54.13 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P11166 (Residues: 1-492; Coverage: 100%)
Gene names: GLUT1, SLC2A1
Sequence domains: Sugar (and other) transporter
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2
Unit cell:
a: 122.43Å b: 102.31Å c: 68.073Å
α: 90° β: 100.16° γ: 90°
R-values:
R R work R free
0.252 0.247 0.293
Expression system: Saccharomyces cerevisiae