PDBe 5e00

X-ray diffraction
1.7Å resolution

Structure of HLA-A2 P130

Released:
Source organism: Homo sapiens
Entry authors: Zhang Y, Wu Y, Qi J, Liu J, Gao GF, Meng S

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 997 Da
Source organism: Homo sapiens
Expression system: Not provided
HLA class I histocompatibility antigen, A-2 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01892 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-A, HLAA
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 48.608Å b: 72.006Å c: 123.788Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.176 0.205
Expression systems:
  • Escherichia coli
  • Not provided