PDBe 5dfv

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH MURINE FAB FRAGMENT K04

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
CD81 antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 99 amino acids
Theoretical weight: 10.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P60033 (Residues: 112-202; Coverage: 39%)
Gene names: CD81, TAPA1, TSPAN28
Structure domains: Tetraspanin
FAB HEAVY CHAIN Chains: C, E
Molecule details ›
Chains: C, E
Length: 222 amino acids
Theoretical weight: 23.45 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
FAB LIGHT CHAIN Chains: D, F
Molecule details ›
Chains: D, F
Length: 218 amino acids
Theoretical weight: 24.19 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 77.631Å b: 94.483Å c: 94.114Å
α: 90° β: 104.14° γ: 90°
R-values:
R R work R free
0.242 0.239 0.291
Expression system: Escherichia coli