PDBe 5bpb

X-ray diffraction
2.2Å resolution

Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form I

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Frizzled-4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 149 amino acids
Theoretical weight: 16.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9ULV1 (Residues: 42-179; Coverage: 28%)
Gene name: FZD4
Sequence domains: Fz domain
Structure domains: Frizzled cysteine-rich domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P212121
Unit cell:
a: 72.608Å b: 102.14Å c: 116.508Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.223
Expression system: Homo sapiens