PDBe 5b83

X-ray diffraction
2.69Å resolution

Crystal structure of Optineurin UBAN in complex with linear ubiquitin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin Chains: A, D
Molecule details ›
Chains: A, D
Length: 304 amino acids
Theoretical weight: 34.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CG48 (Residues: 381-684; Coverage: 44%)
Gene name: UBC
Sequence domains: Ubiquitin family
Optineurin Chains: B, C, E, F
Molecule details ›
Chains: B, C, E, F
Length: 102 amino acids
Theoretical weight: 11.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96CV9 (Residues: 416-510; Coverage: 17%)
Gene names: FIP2, GLC1E, HIP7, HYPL, NRP, OPTN

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 71.327Å b: 82.038Å c: 244.853Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.254
Expression system: Escherichia coli