PDBe 5aef

Electron Microscopy
5Å resolution

Electron cryo-microscopy of an Abeta(1-42)amyloid fibril

Released:
Source organism: Homo sapiens
Primary publication:
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
Proc. Natl. Acad. Sci. U.S.A. 112 11858-63 (2015)
PMID: 26351699
Related structures: EMD-3132

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
P3(42) Chains: A, B
Molecule details ›
Chains: A, B
Length: 28 amino acids
Theoretical weight: 2.84 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 686-713; Coverage: 4%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-3132
Expression system: Not provided