PDBe 5abd

X-ray diffraction
2Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vascular endothelial growth factor receptor 1 Chains: E, I, X
Molecule details ›
Chains: E, I, X
Length: 95 amino acids
Theoretical weight: 10.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW P17948 (Residues: 132-226; Coverage: 7%)
Gene names: FLT, FLT1, FRT, VEGFR1
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: I222
Unit cell:
a: 62.547Å b: 66.189Å c: 176.477Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.178 0.222
Expression system: Escherichia coli BL21(DE3)