PDBe 4xki

X-ray diffraction
2Å resolution

Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R

Released:
Source organism: Homo sapiens
Entry author: Xia X

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 147 amino acids
Theoretical weight: 16.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05230 (Residues: 16-155; Coverage: 90%)
  • Best match: P05230-2 (Residues: 16-56)
Gene names: FGF1, FGFA
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2221
Unit cell:
a: 75.624Å b: 96.274Å c: 109.525Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.175 0.215
Expression system: Escherichia coli BL21(DE3)