› 4w8h

X-ray diffraction
1.14Å resolution

Crystal structure of the TIR domain of the Toll-related Receptor TRR-2 from the lower metazoan Hydra magnipapillata (crystal form II)

Released:
DOI: 10.2210/pdb4w8h/pdb
PDB entry 4w8h coloured by chain, front view.
PDB entry 4w8h coloured by chain, side view.
PDB entry 4w8h coloured by chain, top view.
Source organisms:
Entry authors: Weisse RH-J, Scheidig AJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107982 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TIR domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 15.33 KDa
Source organism: Hydra vulgaris
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A6M946 (Residues: 95-221; Coverage: 58%)
Gene name: TRR-2
Sequence domains: TIR domain
Structure domains: Toll/interleukin-1 receptor homology (TIR) domain
hexa-His tag Chain: D
Molecule details ›
Chain: D
Length: 6 amino acids
Theoretical weight: 847 Da
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 30.73Å b: 63.57Å c: 32.12Å
α: 90° β: 105.17° γ: 90°
R-values:
R R work R free
0.142 0.14 0.171
Expression system: Escherichia coli BL21(DE3)

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