› 4w1u

X-ray diffraction
1.88Å resolution

Crystal structure of Rv3557c/KstR2, a transcriptional repressor involved in cholesterol metabolism in Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb4w1u/pdb
PDB entry 4w1u coloured by chain, front view.
PDB entry 4w1u coloured by chain, side view.
PDB entry 4w1u coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry authors: Dawes SS, Kendall SK, Baker EN, Lott JS

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161780 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional repressor KstR2 Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 23.25 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P9WMB9 (Residues: 1-200; Coverage: 100%)
Gene names: Rv3557c, kstR2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 72.356Å b: 90.292Å c: 49.693Å
α: 90° β: 128.21° γ: 90°
R-values:
R R work R free
0.173 0.172 0.2
Expression system: Escherichia coli BL21

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