PDBe 4tqx

X-ray diffraction
1.37Å resolution

Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sortase A Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 22.74 KDa
Source organism: Streptococcus mutans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8CM62 (Residues: 41-246; Coverage: 84%)
Gene name: srtA
Sequence domains: Sortase domain

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P42212
Unit cell:
a: 82.822Å b: 82.822Å c: 57.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 0.145 0.179
Expression system: Escherichia coli BL21(DE3)