› › Function and Biology

Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin

Source organisms:
Biochemical function: hormone activity
Biological process: transmembrane transport
Cellular component: extracellular region

Quick links

GO terms

Sequence families

Pfam Protein families (Pfam)
PF02793
Domain description: Hormone receptor domain
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
The deposited structure of PDB entry 4rwf contains 1 copy of Pfam domain PF02793 (Hormone receptor domain) in Calcitonin gene-related peptide type 1 receptor. Showing 1 copy in chain A.

PF04901
Domain description: Receptor activity modifying family
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
The deposited structure of PDB entry 4rwf contains 1 copy of Pfam domain PF04901 (Receptor activity modifying family) in Calcitonin gene-related peptide type 1 receptor. Showing 1 copy in chain A.

PF01547
Domain description: Bacterial extracellular solute-binding protein
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
The deposited structure of PDB entry 4rwf contains 1 copy of Pfam domain PF01547 (Bacterial extracellular solute-binding protein) in Calcitonin gene-related peptide type 1 receptor. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006060
Domain description: Maltose/Cyclodextrin ABC transporter, substrate-binding protein
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR001879
Domain description: GPCR, family 2, extracellular hormone receptor domain
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR001710
Domain description: Pro-adrenomedullin
Occurring in:
  1. Adrenomedullin
IPR036445
Domain description: GPCR family 2, extracellular hormone receptor domain superfamily
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR021116
Domain description: Calcitonin/adrenomedullin
Occurring in:
  1. Adrenomedullin
IPR017983
Domain description: GPCR, family 2, secretin-like, conserved site
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR006985
Domain description: Receptor activity modifying protein
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR038126
Domain description: RAMP domain superfamily
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR006061
Domain description: Solute-binding family 1, conserved site
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
IPR006059
Domain description: Bacterial-type extracellular solute-binding protein
Occurring in:
  1. Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2

Quick links