› 4rmv

X-ray diffraction
1.46Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158314 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2-microglobulin Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 11.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand ACT 1 x ACT
Ligand PGE 1 x PGE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 77.54Å b: 28.871Å c: 53.28Å
α: 90° β: 125.78° γ: 90°
R-values:
R R work R free
0.19 0.186 0.229
Expression system: Escherichia coli

Quick links

Citations

4 review citations

1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning.
Le Marchand et al. (2022)
3 more

1 mention without citation

Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Le Marchand et al. (2018)