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Crystal structure of the D76E Beta-2 Microglobulin mutant

X-ray diffraction
1.4Å resolution
PDB entry 4rmu coloured by chain, front view.
PDB entry 4rmu coloured by chain, side view.
PDB entry 4rmu coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Beta-2-microglobulin
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Multimeric state: monomeric
Accessible surface area: 6715.96 Å2
Buried surface area: 234.83 Å2
Dissociation area: 117.42 Å2
Dissociation energy (ΔGdiss): -2.38 kcal/mol
Dissociation entropy (TΔSdiss): 2.41 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158314

Macromolecules

Beta-2-microglobulin
Chain: A
Length: 100 amino acids
Theoretical weight: 11.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Beta-2-microglobulin in PDB entry 4rmu, assembly 1, front view.
Beta-2-microglobulin in PDB entry 4rmu, assembly 1, side view.
Beta-2-microglobulin in PDB entry 4rmu, assembly 1, top view.
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