PDBe 4qqe

X-ray diffraction
1.8Å resolution

Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345

Released:
Entry authors: Dong A, Dombrovski L, Wernimont A, Smil D, Getlik M, Senisterra G, Poda G, Al-Awar R, Bountra C, Arrowsmith CH, Edwards AM, Brown PJ, Schapira M, Vedadi M, Wu H, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 80.896Å b: 85.267Å c: 40.209Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.173 0.218