PDBe 4prg

X-ray diffraction
2.9Å resolution

0072 PARTIAL AGONIST PPAR GAMMA COCRYSTAL

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor gamma Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 270 amino acids
Theoretical weight: 30.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P37231 (Residues: 235-504; Coverage: 54%)
Gene names: NR1C3, PPARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P2
Unit cell:
a: 92.72Å b: 61.54Å c: 118.81Å
α: 90° β: 102.57° γ: 90°
R-values:
R R work R free
0.24 0.24 0.283
Expression system: Escherichia coli