Function and Biology

The longer crystal structure of the grow factor like domain from Beta amypoid precusor protein (APP22-126)

Source organism: Homo sapiens
Biochemical function: heparin binding
Biological process: not assigned
Cellular component: membrane

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF02177
Domain description: Amyloid A4 N-terminal heparin-binding
Occurring in:
  1. N-APP
The deposited structure of PDB entry 4pqd contains 1 copy of Pfam domain PF02177 (Amyloid A4 N-terminal heparin-binding) in N-APP. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR008154
Domain description: Amyloidogenic glycoprotein, extracellular
Occurring in:
  1. N-APP
IPR036454
Domain description: Amyloidogenic glycoprotein, heparin-binding domain superfamily
Occurring in:
  1. N-APP
IPR015849
Domain description: Amyloidogenic glycoprotein, heparin-binding
Occurring in:
  1. N-APP
IPR008155
Domain description: Amyloidogenic glycoprotein
Occurring in:
  1. N-APP

Structure domain

CATH CATH domain
3.90.570.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Sugar Binding Protein, Amyloid A4 Protein; Chain A
Homology: Amyloidogenic glycoprotein, heparin-binding domain
Occurring in:
  1. N-APP
The deposited structure of PDB entry 4pqd contains 1 copy of CATH domain 3.90.570.10 (Sugar Binding Protein, Amyloid A4 Protein; Chain A) in N-APP. Showing 1 copy in chain A.