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The longer crystal structure of the grow factor like domain from Beta amypoid precusor protein (APP22-126)

X-ray diffraction
1.332Å resolution
PDB entry 4pqd coloured by chain, front view.
PDB entry 4pqd coloured by chain, side view.
PDB entry 4pqd coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Soluble APP-beta
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-138353

Macromolecules

N-APP
Chain: A
Length: 105 amino acids
Theoretical weight: 11.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05067 (Residues: 22-126; Coverage: 14%)
Gene names: A4, AD1, APP
Pfam: Amyloid A4 N-terminal heparin-binding
InterPro:
CATH: Amyloidogenic glycoprotein, heparin-binding domain
N-APP in PDB entry 4pqd, assembly 1, front view.
N-APP in PDB entry 4pqd, assembly 1, side view.
N-APP in PDB entry 4pqd, assembly 1, top view.
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