PDBe 4mvt

X-ray diffraction
2.3Å resolution

Crystal structure of SUMO E3 Ligase PIAS3

Released:
Source organism: Homo sapiens
Entry authors: Dong A, Hu J, Li Y, Tempel W, Bountra C, Arrowsmith CH, Edwards AM, Tong Y, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 SUMO-protein ligase PIAS3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 374 amino acids
Theoretical weight: 41.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9Y6X2 (Residues: 112-467; Coverage: 57%)
Gene name: PIAS3
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P1
Unit cell:
a: 55.45Å b: 85.44Å c: 89.53Å
α: 83.08° β: 86.57° γ: 86.14°
R-values:
R R work R free
0.239 0.238 0.27
Expression system: Escherichia coli BL21