PDBe 4mbs

X-ray diffraction
2.71Å resolution

Crystal Structure of the CCR5 Chemokine Receptor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C chemokine receptor type 5; Rubredoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 414 amino acids
Theoretical weight: 47.52 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P00268 (Residues: 1-54; Coverage: 100%)
  • Canonical: P51681 (Residues: 2-223, 227-352; Coverage: 99%)
  • nullnull
Gene names: CCR5, CMKBR5
Sequence domains:
Structure domains: Rhopdopsin 7-helix transmembrane proteins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 72.92Å b: 103.52Å c: 137.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.263
Expression system: Spodoptera frugiperda