Structure analysis

Human dCK C4S-S74E mutant in complex with UDP and the DI-43 inhibitor

X-ray diffraction
1.94Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Chains: A, B
Length: 280 amino acids
Theoretical weight: 32.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P27707 (Residues: 1-260; Coverage: 100%)
Gene name: DCK
Pfam: Deoxynucleoside kinase
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases

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