PDBe 4l57

X-ray diffraction
1.08Å resolution

High resolutin structure of human cytosolic 5'(3')-deoxyribonucleotidase

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5'(3')-deoxyribonucleotidase, cytosolic type Chains: A, B
Molecule details ›
Chains: A, B
Length: 195 amino acids
Theoretical weight: 22.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8TCD5 (Residues: 1-195; Coverage: 97%)
Gene names: DNT1, NT5C, UMPH2
Sequence domains: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P1
Unit cell:
a: 39.128Å b: 46.493Å c: 61.409Å
α: 68.16° β: 81.47° γ: 75.28°
R-values:
R R work R free
0.144 0.144 0.183
Expression system: Escherichia coli BL21(DE3)