› 4kwm

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111022 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 329 amino acids
Theoretical weight: 37 KDa
Source organism: Influenza A virus (A/chicken/Anhui/1089/2007(H5N1))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: C0LYC6 (Residues: 17-341; Coverage: 57%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin HA2 chain Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 174 amino acids
Theoretical weight: 20.11 KDa
Source organism: Influenza A virus (A/chicken/Anhui/1089/2007(H5N1))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: C0LYC6 (Residues: 346-519; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

1 bound ligand:
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P3
Unit cell:
a: 114.372Å b: 114.372Å c: 134.89Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.208 0.247
Expression system: Trichoplusia ni

Quick links

Citations

1 review citation

Strategies towards universal pandemic influenza vaccines.
He et al. (2016)
14 other articles

3 mentions without citation

Applications of quantum mechanical/molecular mechanical methods to the chemical insertion step of DNA and RNA polymerization.
Perera et al. (2014)
2 more