Structure analysis

Structure of neuronal nitric oxide synthase heme domain in complex with (R)-1,2-bis((2-amino-4-methylpyridin-6-yl)-methoxy)-propan-3-amine

X-ray diffraction
1.892Å resolution
Source organism: Rattus norvegicus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule


Assembly 1 (preferred)
Multimeric state: homo dimer
Accessible surface area: 33100 Å2
Buried surface area: 11500 Å2
Dissociation area: 50 Å2
Dissociation energy (ΔGdiss): 41 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): -134 kcal/mol
Symmetry number: 2


Chains: A, B
Length: 422 amino acids
Theoretical weight: 48.75 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P29476 (Residues: 297-597, 599-718; Coverage: 30%)
Gene names: Bnos, Nos1
Pfam: Nitric oxide synthase, oxygenase domain
InterPro: Nitric oxide synthase, N-terminal

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