PDBe 4jw2

X-ray diffraction
1.9Å resolution

Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
A3 artificial protein Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 11.95 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
bA3-2: binder of A3 protein Chain: B
Molecule details ›
Chain: B
Length: 201 amino acids
Theoretical weight: 22.22 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P43212
Unit cell:
a: 87.76Å b: 87.76Å c: 77.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.194 0.224
Expression system: Escherichia coli