Structure analysis

Crystal Structure of uPA in complex with its inhibitor 4-bromobenzylamine at pH 7.4

X-ray diffraction
2Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: U
Length: 247 amino acids
Theoretical weight: 27.84 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00749 (Residues: 179-425; Coverage: 60%)
Gene name: PLAU
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases

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