PDBe 4jin

X-ray diffraction
2.1Å resolution

X-ray crystal structure of Archaeoglobus fulgidus Rio1 bound to (2E)-N-benzyl-2-cyano-3-(pyridine-4-yl)acrylamide (WP1086)

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RIO-type serine/threonine-protein kinase Rio1 Chain: A
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 30.14 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
  • Canonical: O28471 (Residues: 1-258; Coverage: 100%)
Gene names: AF_1804, rio1
Sequence domains: RIO1 family

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 42.553Å b: 52.608Å c: 63.654Å
α: 90° β: 109.22° γ: 90°
R-values:
R R work R free
0.182 0.179 0.241
Expression system: Escherichia coli