Assemblies
Assembly Name:
Caspase-7 complex and unmapped proteins
Multimeric state:
hetero hexamer
Accessible surface area:
31158.54 Å2
Buried surface area:
16575.13 Å2
Dissociation area:
1,664.65
Å2
Dissociation energy (ΔGdiss):
-12.06
kcal/mol
Dissociation entropy (TΔSdiss):
25.17
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-157243
Macromolecules
Chain: A
Length: 175 amino acids
Theoretical weight: 19.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Caspase domain
InterPro:
Length: 175 amino acids
Theoretical weight: 19.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P55210 (Residues: 24-198; Coverage: 58%)
Pfam: Caspase domain
InterPro:
- Peptidase C14 family
- Caspase-like domain superfamily
- Peptidase C14A, caspase catalytic domain
- Peptidase C14, p20 domain
- Peptidase C14, caspase domain
- Peptidase family C14A, His active site
- Peptidase family C14A, cysteine active site
Chain: B
Length: 105 amino acids
Theoretical weight: 12.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Caspase domain
InterPro:
Length: 105 amino acids
Theoretical weight: 12.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P55210 (Residues: 207-303; Coverage: 32%)
Pfam: Caspase domain
InterPro:
- Caspase-like domain superfamily
- Peptidase C14A, caspase catalytic domain
- Peptidase C14, caspase domain
- Peptidase C14, caspase non-catalytic subunit p10
Chain: P
Length: 171 amino acids
Theoretical weight: 18.2 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
CATH: Ankyrin repeat-containing domain
Length: 171 amino acids
Theoretical weight: 18.2 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
CATH: Ankyrin repeat-containing domain
