Function and Biology Details
Reaction catalysed:
L-tyrosine + tetrahydrobiopterin + O(2) = L-dopa + 4a-hydroxytetrahydrobiopterin
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139371 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein gamma
Molecule details ›
Chains: A, B, C, D
Length: 255 amino acids
Theoretical weight: 29.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Length: 255 amino acids
Theoretical weight: 29.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P61981 (Residues: 2-247; Coverage: 100%)
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Tyrosine 3-monooxygenase
Molecule details ›
Chains: E, F, G, H
Length: 43 amino acids
Theoretical weight: 4.86 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: Tyrosine hydroxylase N terminal
Length: 43 amino acids
Theoretical weight: 4.86 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P07101 (Residues: 1-74; Coverage: 8%)
Sequence domains: Tyrosine hydroxylase N terminal
