› 4ivn

X-ray diffraction
1.9Å resolution

The Vibrio vulnificus NanR protein complexed with ManNAc-6P

Released:
DOI: 10.2210/pdb4ivn/pdb
PDB entry 4ivn coloured by chain, front view.
PDB entry 4ivn coloured by chain, side view.
PDB entry 4ivn coloured by chain, top view.
Source organism: Vibrio vulnificus YJ016
Primary publication:
Structural insights into the regulation of sialic acid catabolism by the Vibrio vulnificus transcriptional repressor NanR.
Hwang J, Kim BS, Jang SY, Lim JG, You DJ, Jung HS, Oh TK, Lee JO, Choi SH, Kim MH
Proc Natl Acad Sci U S A 110 E2829-37 (2013)
PMID: 23832782

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181720 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 278 amino acids
Theoretical weight: 30.34 KDa
Source organism: Vibrio vulnificus YJ016
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7MD38 (Residues: 1-278; Coverage: 100%)
Gene name: VVA1198
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand BMX 2 x BMX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P3121
Unit cell:
a: 109.205Å b: 109.205Å c: 82.472Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.181 0.235
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Host Sialic Acids: A Delicacy for the Pathogen with Discerning Taste.
Haines-Menges et al. (2015)
2 more

4 mentions without citation

One ligand, two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas.
Campilongo et al. (2017)
3 more