4iva Experiments and Validation

X-ray diffraction

Entry percentile scores
Source organism: Homo sapiens [9606]
Resolution: 1.5Å
Reported R values:
R Rwork Rfree
0.176 0.175 0.193

Sample information

Author description:
JAK2 kinase (JH1 domain) in complex with the inhibitor TRANS-4-[(8AS)-2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(8AH)-YL]CYCLOHEXANECARBONITRILE
Source organism: Homo sapiens [9606]
Expression system: Spodoptera frugiperda [7108]

Validation information

Experimental information

Dataset statistics
Refinement statistics