Function and Biology

Crystal structure of the RRM domain of RNA helicase HERA from T. thermophilus in complex with GGGC RNA

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.6.4.13: RNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate.
Comments:
  • RNA helicases utilize the energy from ATP hydrolysis to unwind RNA.
  • Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity.
  • Some helicases unwind DNA as well as RNA.
  • May be identical with EC 3.6.4.12 (DNA helicase).
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
  • CSFV NS3 helicase
  • DBP2
  • DbpA
  • DDX17
  • DDX25
  • DDX3
  • DDX3X
  • DDX3Y
  • DDX4
  • DDX5
  • DEAD-box protein DED1
  • DEAD-box RNA helicase
  • DEAH-box protein 2
  • DEAH-box RNA helicase
  • DED1
  • Dex(H/D) RNA helicase
  • EhDEAD1
  • EhDEAD1 RNA helicase
  • EIF4A helicase
  • KOKV helicase
  • Mtr4p
  • Nonstructural protein 3 helicase
  • NPH-II
  • RHA
  • RNA helicase A
  • RNA helicase DDX3
  • RNA helicase Hera
  • RNA-dependent ATPase
  • TGBp1 NTPase/helicase domain
  • VRH1
  • GRTH/DDX25

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned