PDBe 4i56

X-ray diffraction
1.5Å resolution

HMG-CoA reductase from pseudomonas mevalonii complexed with dithio-HMG-coa

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-hydroxy-3-methylglutaryl-coenzyme A reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 428 amino acids
Theoretical weight: 45.64 KDa
Source organism: Pseudomonas mevalonii
Expression system: Escherichia coli
UniProt:
  • Canonical: P13702 (Residues: 1-428; Coverage: 100%)
Gene name: mvaA
Sequence domains: Hydroxymethylglutaryl-coenzyme A reductase
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: I4132
Unit cell:
a: 226.082Å b: 226.082Å c: 226.082Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.168 0.189
Expression system: Escherichia coli