Structure analysis

Crystal structure of CYP3A4 ligated to pyridine-substituted desoxyritonavir

X-ray diffraction
2.9Å resolution
Source organism: Homo sapiens
Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly
Assembly 2
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Multimeric state: homo tetramer

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 487 amino acids
Theoretical weight: 55.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08684 (Residues: 21-503; Coverage: 96%)
Gene names: CYP3A3, CYP3A4
Pfam: Cytochrome P450
InterPro:
CATH: Cytochrome p450

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