EC 22.214.171.124: Macrophage elastase
Hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in the B chain of insulin.
- Belongs to peptidase family M10B.
- Human macrophage metalloelastase (HME)
- Matrix metalloproteinase 12
Protein family (Pfam)
Domain description: Peptidase M10, metallopeptidase