PDBe 4h3b

X-ray diffraction
2.08Å resolution

Crystal Structure of JNK3 in Complex with SAB Peptide

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SH3 domain-binding protein 5 Chains: B, D
Molecule details ›
Chains: B, D
Length: 10 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O60239 (Residues: 341-350; Coverage: 2%)
Gene names: SAB, SH3BP5
Mitogen-activated protein kinase 10 Chains: A, C
Molecule details ›
Chains: A, C
Length: 356 amino acids
Theoretical weight: 41.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53779 (Residues: 45-400; Coverage: 77%)
Gene names: JNK3, JNK3A, MAPK10, PRKM10, SAPK1B
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P31
Unit cell:
a: 84.52Å b: 84.52Å c: 127.25Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.186 0.235
Expression systems:
  • Not provided
  • Escherichia coli