PDBe 4h1y

X-ray diffraction
1.58Å resolution

Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with PSB11552

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5'-nucleotidase Chain: P
Molecule details ›
Chain: P
Length: 546 amino acids
Theoretical weight: 60.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21589 (Residues: 27-549; Coverage: 95%)
Gene names: NT5, NT5E, NTE
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21212
Unit cell:
a: 67.483Å b: 131.893Å c: 66.333Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.171 0.196
Expression system: Escherichia coli