› 4gn8

X-ray diffraction
1.7Å resolution

Function and Biology Details

Reaction catalysed: 
D-glucono-1,5-lactone + H(2)O = D-gluconate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regucalcin Chains: A, B
Molecule details ›
Chains: A, B
Length: 299 amino acids
Theoretical weight: 33.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q64374 (Residues: 1-299; Coverage: 100%)
Gene names: Rgn, Smp30
Sequence domains: SMP-30/Gluconolactonase/LRE-like region
Structure domains: TolB, C-terminal domain

Ligands and Environments

3 bound ligands:
Ligand CA 2 x CA
Ligand SO4 13 x SO4
Ligand ASO 9 x ASO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P3121
Unit cell:
a: 102.587Å b: 102.587Å c: 149.706Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.17 0.19
Expression system: Escherichia coli

Quick links

Citations

11 citation in other articles

Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis.
Kondo et al. (2014)
10 more

3 mentions without citation

Structure and function of aldopentose catabolism enzymes involved in oxidative non-phosphorylative pathways.
Ren et al. (2022)
2 more