PDBe 4gmb

X-ray diffraction
2.78Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MM-402 Chain: E
Molecule details ›
Chain: E
Length: 5 amino acids
Theoretical weight: 634 Da
Source organism: Synthetic construct
Expression system: Not provided
WD repeat-containing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 313 amino acids
Theoretical weight: 34.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P61964 (Residues: 22-334; Coverage: 94%)
Gene names: BIG3, WDR5
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

No bound ligands

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 47.297Å b: 50.837Å c: 137.845Å
α: 90° β: 90° γ: 90°
R R work R free
0.192 0.19 0.247
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)