PDBe 4gg6

X-ray diffraction
3.2Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
T-cell receptor beta-1 chain C region Chains: F, H
Molecule details ›
Chains: F, H
Length: 245 amino acids
Theoretical weight: 27.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01850 (Residues: 1-130; Coverage: 73%)
Gene name: TRBC1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
T-cell receptor, sp3.4 alpha chain Chains: E, G
Molecule details ›
Chains: E, G
Length: 207 amino acids
Theoretical weight: 23.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: K7N5N2 (Residues: 1-207; Coverage: 100%)
Sequence domains:
Structure domains: Immunoglobulins
Alpha/beta-gliadin MM1 Chains: I, J
Molecule details ›
Chains: I, J
Length: 18 amino acids
Theoretical weight: 2.01 KDa
Source organism: Triticum aestivum
Expression system: Not provided
UniProt:
  • Canonical: P18573 (Residues: 243-260; Coverage: 6%)
HLA class II histocompatibility antigen, DQ beta 1 chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 215 amino acids
Theoretical weight: 24.61 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P01920 (Residues: 33-224; Coverage: 84%)
Gene names: HLA-DQB, HLA-DQB1
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DQ alpha 1 chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 192 amino acids
Theoretical weight: 21.87 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P01909 (Residues: 24-78, 79-206; Coverage: 79%)
Gene name: HLA-DQA1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P212121
Unit cell:
a: 111.708Å b: 134.325Å c: 140.304Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.246 0.285
Expression systems:
  • Escherichia coli
  • Not provided
  • Trichoplusia ni