› 4gci

X-ray diffraction
1.5Å resolution

Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target EFI-501894, with bound glutathione, monoclinic form

Released:
DOI: 10.2210/pdb4gci/pdb
PDB entry 4gci coloured by chain, front view.
PDB entry 4gci coloured by chain, side view.
PDB entry 4gci coloured by chain, top view.
Source organism: Yersinia pestis
Entry authors: Vetting MW, Toro R, Bhosle R, Al Obaidi NF, Morisco LL, Wasserman SR, Sojitra S, Washington E, Scott Glenn A, Chowdhury S, Evans B, Hammonds J, Hillerich B, Love J, Seidel RD, Imker HJ, Armstrong RN, Gerlt JA, Almo SC, Enzyme Function Initiative (EFI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184032 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathionine S-transferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 211 amino acids
Theoretical weight: 23.79 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8D0L3 (Residues: 1-202; Coverage: 100%)
Gene names: YP_2153, gst, gst2, y1968
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand GSH 2 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 48.741Å b: 89.338Å c: 57.546Å
α: 90° β: 112.26° γ: 90°
R-values:
R R work R free
0.177 0.176 0.208
Expression system: Escherichia coli BL21(DE3)

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