Structure analysis

Human topoisomerase iibeta in complex with DNA and ametantrone

X-ray diffraction
2.696Å resolution
Assembly composition:
hetero hexamer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero hexamer

Binding statistics and energies are not available for this assembly

Macromolecules

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Name: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3')
Representative chains: C, E
Source organism: Synthetic construct [32630]
Expression system: Not provided
Length: 8 nucleotides
Theoretical weight: 2.44 KDa

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Name: DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3')
Representative chains: D, F
Source organism: Synthetic construct [32630]
Expression system: Not provided
Length: 12 nucleotides
Theoretical weight: 3.65 KDa

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